If you are saving your important data files outside of your user profile, you can go with Custom Libraries that ensures you that those files are always backed up. Therefore, you can create a new library, call it Backup, and ensure it is selected in your current backup settings. Moreover, you can add locations to the new library that you want to ensure are backed up. At the same time, the files remain in their original locations and they will be backed up as long as they are on a local drive.
